Spondylolisthesis is a spinal condition where one of the vertebrae slips out of its normal position onto the bone below it. The slippage puts pressure on the nerves and can cause symptoms like back pain and numbness/tingling in the legs.
Anatomy and Function of the Spine
The spine is a complex structure made up of 33 vertebrae interlocked with cartilage discs and facet joints, held together by ligaments and muscles. This intricate design allows flexibility and support for the upper body.
The Vertebral Column
The 33 vertebrae are grouped into sections – 7 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 4 coccygeal. The lumbar vertebrae in the lower back bear the most weight and are common areas for spondylolisthesis.
Intervertebral Discs
Between vertebrae are discs made of cartilage with a gel-like core. These cushion vertebrae, prevent friction, and provide flexibility.
Facet Joints
Every vertebra has four facet joints linking it to neighboring vertebrae. These allow back motion and spinal stability.
Spinal Stability
Many components enable spine flexibility plus support body weight: vertebrae, facet joints, discs, ligaments and muscles. Imbalance stresses areas like lumbar vertebrae.
Spinal Cord and Nerves
The spinal cord runs through the vertebral foramen, carrying nerves linking the brain and body. Nerves exit at each vertebral level. Slippage can pinch nerves.
Types of Spondylolisthesis
There are five main types of spondylolisthesis, each with their own causes and characteristics:
Dysplastic Spondylolisthesis
This type occurs due to a congenital defect in the pars interarticularis region of the vertebrae, which are small bones that connect the facet joints. Since the spine does not form properly before birth, it is left vulnerable to slipping later in life. Dysplastic spondylolisthesis most commonly occurs between L5 and S1 vertebrae.
Isthmic Spondylolisthesis
Also called spondylolytic spondylolisthesis. This happens when there is a stress fracture in the pars interarticularis of the vertebrae, usually at L5-S1. This fracture weakens the bone and can lead to slippage. It’s common in young athletes who participate in sports with repetitive hyperextension and rotation.
Degenerative Spondylolisthesis
This is the most common type, happening in older adults due to aging/degenerative changes in the spine. As the disks between vertebrae wear down and facet cartilage erodes, the bones become more likely to slip forward. Degenerative spondylolisthesis happens most frequently between L4-L5.
Traumatic Spondylolisthesis
This rare type is caused by an acute injury leading to a fracture in part of the vertebrae, like the pedicle or facet joints. The fracture causes sudden instability and slippage.
Pathologic Spondylolisthesis
This happens due to an underlying disease weakening the spine, like osteoporosis, or from a tumor eroding the bone. Anything compromising vertebral integrity can produce slippage.
The location in spine, cause, and grade of slippage influences symptoms and ideal treatments for each type.
Causes and Risk Factors
There are several potential causes and risk factors for developing spondylolisthesis:
Sports Injuries and Overuse
Activities like gymnastics and football that hyperextend the spine can lead to stress fractures and eventual slippage. Growth spurts in adolescence can also be a contributing factor.
Genetics/Congenital Factors
Some people are just born with a higher risk. Thinner sections of vertebrae or general instability in the spine passed down genetically can predispose someone.
Aging and Degeneration
As spinal disks wear down from osteoarthritis and other age-related changes, the vertebrae become more likely to slip. Over 50% of cases occur in adults over 60.
Spinal Defects and Fractures
Defects like spondylolysis (crack in vertebra) or previous vertebral fractures place more stress on that area of spine and contribute to slippage.
Bone Disease/Spinal Tumors
Conditions like osteoporosis or spinal tumors can weaken vertebral bone and cause it to slip.
Those at highest risk: young athletes, individuals with family history, and adults over 50.
Symptoms
Possible symptoms include:
Back Pain
Most common complaint, typically worse with activity and better with rest. Can range from mild chronic pain to severe debilitating pain.
Leg Pain or Numbness
Slippage presses on spinal nerves, causing sciatica-like pain down the legs or numbness/tingling.
Muscle Tightness
Especially in the hamstrings and lower back as those muscles try to stabilize the spine.
Mobility Issues
Changes to normal spinal alignment impacts posture, gait and flexibility. Standing, walking and bending over can become difficult.
Bowel/Bladder Problems
Severe slippage compromises signals to/from bowel and bladder, causing incontinence in some cases.
Asymptomatic
Many spondylolisthesis cases cause no symptoms initially and are picked up incidentally on imaging for other reasons.
Diagnosis and Grading
To diagnose spondylolisthesis, providers use:
Physical Exam
Checking range of motion, areas of tenderness, muscle tightness, strength, reflexes and nerve function.
Imaging Studies
X-rays show slippage and alignment issues. CT scans and MRIs allow closer look at disks, nerves and soft tissues.
Severity Measurements
Slippage percentage determines grade from 1-4. Higher grades indicate greater instability and risk of symptoms/complications.
It’s crucial to distinguish spondylolisthesis from other conditions like slipped discs that can cause similar pain.
Treatment Options
Many treatment routes exist depending on grade of slippage and symptoms:
Lifestyle Changes
Sometimes rest, activity modification and posture correction does the trick.
Medications
Anti-inflammatories and muscle relaxants can alleviate pain and spasms.
Steroid Injections
Injections directly into spine temporarily reduce inflammation pressing on nerves.
Braces and Physical Therapy
Helps stabilize spine and build supporting muscle strength.
Decompression Surgery
Removes bone/disc material to create space for nerve roots.
Spinal Fusion Techniques
Several methods permanently join problematic vertebrae to prevent further slippage. Adding rods, screws or bone graft provides stability.
Outlook and Prevention
When needed, surgery boasts excellent outcomes. Still, it’s smart to take preventative measures:
Surgery Success
Most patients experience significant pain/symptom relief and can return to normal function after recovery period.
Preventing Recurrence
Regular strength training and checkups to catch progression early helps avoid repeat slippage.
Risk Reduction Tips
Minding posture, keeping active and fit, avoiding hyperextension activities can help lower odds of developing spondylolisthesis.
Conclusion
Spondylolisthesis has various causes but all involve some instability and slippage of the spinal vertebrae. While often asymptomatic initially, compression on the nerve roots can eventually trigger uncomfortable symptoms. Non-surgical care revolves around pain relief and muscle strengthening. For high-grade slippages causing marked symptoms, spinal fusion procedures usually eradicate pain and restore mobility quite well. Since aging degeneration is the most prevalent factor, everyone can benefit from building core/back strength and making spine-healthy lifestyle choices.
Written by Dr. Tony Mork
Orthopedic Spine Surgeon
I’m Dr. Tony Mork, MD, a Minimally Invasive Orthopedic Spine Surgery Specialist in Newport Beach, California. With over 40 years of experience, I’m dedicated to providing information for all topics that involve neck and back pain.
February 9, 2024
Contact a Spine Specialist Near You!
Related Articles
Lower Back Pain | An Overview
Lower back pain is an exceedingly common affliction that affects up to 80% of adults at some point in their lives. Understanding the underlying causes of lower back pain is key to finding the appropriate treatment and relief. Anatomy of the Lower Back The lower back,...
Degenerative Disc Disease | Causes and Risk Factors
Degenerative disc disease describes age-related wear and tear to the rubbery spinal discs cushioning the vertebrae that can lead to chronic back or neck pain. While partly genetic, there are also lifestyle factors and injuries that accelerate disc degeneration over...
Upper (Thoracic) Back Pain | What is Causing My Pain?
Upper back pain is a surprisingly common affliction, affecting up to one-quarter of the adult population at some point. While not as prevalent as lower back pain, discomfort in the thoracic region still accounts for a substantial slice of musculoskeletal complaints...